Always feeling hungry no matter how much you eat? Struggling with stubborn belly fat, poor digestion, and sluggish metabolism? If you've tried dieting, counting calories, or endless workouts — only to see your weight bounce back — you're not alone. Modern lifestyles, ultra-processed foods, and chronic stress have silently disrupted the GLP-1 pathway — a key metabolic hormone that regulates appetite, fullness, and blood sugar.
On July 25th, 2025, LOTFLY unveiled its breakthrough in metabolic health — the GLP-1 15-in-1 Complex. This daily powder supplement is designed for those who want to restore balance from within — naturally, safely, and without injections. By activating the GLP-1 pathway with 15 ingredients, it helps regulate hunger, improve blood sugar control, and boost metabolic performance — all while supporting gut health and digestive comfort.
What Makes It Different: Science Meets Simplicity
The core of this innovation is the pasteurized Akkermansia muciniphila strain — a next-generation postbiotic with over 1,500 research publications and coverage in leading journals like Nature, Science, and Cell. In a 12-week clinical trial, this strain was shown to increase GLP-1 secretion, leading to an average weight loss of 2.27 kg and a 28.62% improvement in insulin sensitivity.
To amplify its effects, the formula combines 14 other GLP-1 supportive ingredients, including yerba mate extract, apple cider vinegar powder, prebiotic fibers, and postbiotic boosters — all carefully dosed for maximum synergy.
Compared to traditional capsules, this powder strip format is more enjoyable, fast-absorbing, and flexible. Lightly sweetened and flavor-neutral, it blends effortlessly into coffee, tea, or smoothies — making it easy to stay consistent and compliant, even on busy days.
Why Akkermansia Is a Game Changer
Unlike live probiotics, the pasteurized form of Akkermansia offers better stability, safety, and shelf-life — with no refrigeration required. It’s suitable for a broader range of users and integrates seamlessly into daily routines.
Scientific research has confirmed that low Akkermansia levels are strongly linked to obesity, type 2 diabetes, and metabolic syndrome. By replenishing this key strain in postbiotic form, the GLP-1 15-in-1 Complex helps restore the gut–metabolism connection from the root.
When to Use It
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When emotional eating or cravings derail your progress
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During weight-loss plateaus or when satiety feels impossible
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If you experience post-meal blood sugar crashes or fatigue
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When bloating or digestive imbalance affects daily comfort
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For adults 50+ seeking to maintain metabolic health without harsh interventions
A Message From Our Science Team
“At LOTFLY, we believe lasting change doesn’t come from restriction or injections — it starts with restoring balance from within,” said Dr. Amanda Li, Chief Scientific Officer. “We developed the GLP-1 15-in-1 Complex for those who are tired of rebound diets and frustrated with metabolic resistance. Our mission is to offer a natural, science-backed path to satiety, stability, and self-confidence — so people can live with more freedom, energy, and joy.”
Function – Mechanism – Who It’s For
| Function | Mechanism | Target Users |
| Reduce Appetite | Acts on hypothalamus to lower hunger signals | Emotional eaters, overweight individuals |
| Delay Gastric Emptying | Slows digestion to prolong satiety | Those who feel hungry soon after meals |
| Enhance Insulin Secretion | Boosts post-meal insulin release | People with unstable blood sugar or pre-diabetes |
| Improve Insulin Sensitivity | Lowers fat accumulation & boosts efficiency | Individuals with visceral fat or fatty liver |
| Strengthen Gut Microbiome | AKK postbiotics + prebiotics rebalance gut | High-sugar diets, bloating, poor digestion |
Bullet Point Summary
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Naturally supports appetite regulation and satiety
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Helps slow digestion to reduce meal frequency and portions
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Supports healthy insulin release and glucose balance
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Improves insulin sensitivity to support weight and fat metabolism
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Strengthens gut microbiota to boost GLP-1 production naturally